English: Illuminated signs at Piccadilly Circus in September 2012.

Coca-Cola has had a sign at Piccadilly Circus since 1956.

Hyundai Motors sign is the newest of the six, launching on 29 September 2011. It replaced a sign for Sanyo which had occupied the space unchanged since 1987, the last to be run by traditional neon lights rather than Hyundai's computerised LED screen. Earlier Sanyo signs with older logos had occupied the position since 1978, although these were only half the size of the current space.

TDK added its sign in 1990, the space having been previously used by Schweppes (1920-61), BP (1961-7), Cinzano (1967-78), Fujifilm (1978-86) and Kodak (1986-90). The original neon sign remained almost unchanged for twenty years, although in 2001, the colour of the background lamps was changed from green to blue, and the words "Audio & Video Tape" and "Floppy Disks" under the TDK logo were removed. In 2010, the sign was replaced by an LED screen.

McDonald's added its sign in 1987, replacing one for BASF. The sign was changed from neon to LED in 2001. A bigger, brighter screen was installed in 2008.

Samsung added its sign in November 1994, the space having been previously occupied by Canon (1978-84) and Panasonic (1984-94). The sign was changed from neon to LED in summer 2005. The screen was upgraded and improved in autumn 2011.